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Nineteen patients with malignant diseases and pathologically enhancing meninges were studied by pre-and postcontrast(Gd-diethylene-triamine pentaacetic acid)magnetic resonance(MR)scans.Two patterns of enhancement were recognized:the dural(14 patients)and the leptomeningeal(mainly pial) (5 patients).Positive cytology was found in only 3 of the 14 patients with dural enhancement(21%),whereas in the remaining 11 patients we noted either nonspecific CSF findings such as elevated protein,high white blood cell count,and low glucose or entirely normal CSF.Four patients(80%)in the group with leptomeningeal enhancement showed positive cytology and one had normal CSF analysis.We conclude that meningeal enhancement as seen on MR imaging is a nonspecific finding and correlated well with positive cytology only when the more rare form of leptomeningeal enhancement is encountered. |
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cerebrospinal fluid
cerebrospinal fluid,abnormal
cerebrospinal fluid,cytology
cerebrospinal fluid,cytology,false negative
gadolinium
meningeal enhancement
meninges
meningitis,carcinomatous
meningitis,leukemic
meningitis,lymphomatous
MRI
MRI,abnormal
MRI,contrast enhanced
neoplasm,metastatic to Dura
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